@article {1716,
	title = {Stereochemical studies of adrenergic drugs. Optically active derivatives of imidazolines.},
	journal = {J Med Chem},
	volume = {19},
	year = {1976},
	month = {1976 Dec},
	pages = {1382-4},
	abstract = {<p>The synthesis of (R)-(+)-4-methyl-2-(1-naphthylmethyl)imidazoline hydrochloride (2) and (S)-(-)-4-methyl-2-(1-naphthylmethyl)imidazoline hydrochloride (3) is presented. The synthesis involves the preparation of (R)-(+)- and (S)-(-)-1,2-diaminopropane dihydrochloride and then allowing the appropriate diaminopropane to react with ethyl 1-naphthyliminoacetate hydrochloride in the presence of triethylamine. The parent compound, naphazoline, is a potent alpha-adrenoreceptor agonist (-log ED50 = 7.22), whereas the methylated derivatives, 2 and 3, were moderately potent antagonists (pA2 = 5.6 and 5.8, respectively) of the alpha-adrenoreceptor. Compounds 2 and 3 also produced blockade of the response to histamine on the rabbit aorta, but at concentrations approximately 20 times higher than necessary to produce equal blockade of the alpha-adrenoreceptor.</p>},
	keywords = {Animals, Aorta, Histamine H1 Antagonists, Imidazoles, In Vitro Techniques, Muscle, Smooth, Naphazoline, Phenylephrine, Rabbits, Receptors, Adrenergic, Receptors, Adrenergic, alpha, Stereoisomerism},
	issn = {0022-2623},
	author = {Miller, D D and Hsu, F L and Ruffolo, R R and Patil, P N}
}
@article {1740,
	title = {[Acid and alkaline denaturation of superoxide dismutase].},
	journal = {Biofizika},
	volume = {20},
	year = {1975},
	month = {1975 Sep-Oct},
	pages = {783-7},
	abstract = {<p>Optical and ESR spectra of erythrocyte superoxide dismutase denaturated with acid and alkali are described. Sharp changes in activity and spectra were found. "Residual" activity of alkaline denaturated protein was higher than of acidic denaturated sample. It is suggested that covalent bonding copper-nitrogen is essential for superoxide dismutase activity of the protein or synthetic copper complexes.</p>},
	keywords = {Animals, Cattle, Erythrocytes, Hydrogen-Ion Concentration, In Vitro Techniques, Protein Denaturation, Superoxide Dismutase},
	issn = {0006-3029},
	author = {Simonian, M A and Nalbandian, R M}
}
@article {1711,
	title = {Comparison between procaine and isocarboxazid metabolism in vitro by a liver microsomal amidase-esterase.},
	journal = {Biochem Pharmacol},
	volume = {24},
	year = {1975},
	month = {1975 Aug 15},
	pages = {1517-21},
	keywords = {Amidohydrolases, Animals, Esterases, Hydrogen-Ion Concentration, In Vitro Techniques, Isocarboxazid, Kinetics, Male, Metals, Microsomes, Liver, Phospholipids, Procaine, Proteins, Rats, Subcellular Fractions, Temperature},
	issn = {0006-2952},
	author = {Moroi, K and Sato, T}
}
@article {1706,
	title = {Digitoxin metabolism by rat liver microsomes.},
	journal = {Biochem Pharmacol},
	volume = {24},
	year = {1975},
	month = {1975 Sep 1},
	pages = {1639-41},
	keywords = {Animals, Chromatography, Thin Layer, Digitoxigenin, Digitoxin, Hydroxylation, In Vitro Techniques, Male, Microsomes, Liver, NADP, Rats, Time Factors},
	issn = {0006-2952},
	author = {Schmoldt, A and Benthe, H F and Haberland, G}
}
@article {1727,
	title = {Inhibition of aldehyde reductase isoenzymes in human and rat brain.},
	journal = {Biochem Pharmacol},
	volume = {24},
	year = {1975},
	month = {1975 Oct 15},
	pages = {1865-9},
	keywords = {Aldehyde Oxidoreductases, Animals, Anticonvulsants, Barbiturates, Brain, Glutethimide, Humans, Hydantoins, In Vitro Techniques, Isoenzymes, Kinetics, NAD, NADP, Rats, Succinimides},
	issn = {0006-2952},
	author = {Ris, M M and Deitrich, R A and Von Wartburg, J P}
}
@article {1704,
	title = {Maturation of the adrenal medulla--IV. Effects of morphine.},
	journal = {Biochem Pharmacol},
	volume = {24},
	year = {1975},
	month = {1975 Aug 15},
	pages = {1469-74},
	keywords = {Adrenal Medulla, Aging, Animals, Animals, Newborn, Body Weight, Catecholamines, Dopamine beta-Hydroxylase, Epinephrine, Female, Humans, In Vitro Techniques, Maternal-Fetal Exchange, Metaraminol, Morphine, Morphine Dependence, Pregnancy, Rats, Tyrosine 3-Monooxygenase},
	issn = {0006-2952},
	author = {Anderson, T R and Slotkin, T A}
}
